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SMILES: CN(C)CCNC(=O)c1ccc2nnc3-c4ccccc4C(=O)c3c2c1

InChI Key: InChIKey=BNEOGJLFPVMEBB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50240136   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50240136
PNG
(CHEMBL4064044)
Show SMILES CN(C)CCNC(=O)c1ccc2nnc3-c4ccccc4C(=O)c3c2c1
Show InChI InChI=1S/C20H18N4O2/c1-24(2)10-9-21-20(26)12-7-8-16-15(11-12)17-18(23-22-16)13-5-3-4-6-14(13)19(17)25/h3-8,11H,9-10H2,1-2H3,(H,21,26)
PDB

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antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.34E+4n/an/an/an/an/an/a



National and Kapodistrian University of Athens

Curated by ChEMBL


Assay Description
Inhibition of human topoisomerase 2alpha-mediated kinetoplast DNA decatenation after 60 mins by ethidium bromide staining based agarose gel electroph...

Bioorg Med Chem 25: 2625-2634 (2017)


Article DOI: 10.1016/j.bmc.2017.03.019
BindingDB Entry DOI: 10.7270/Q2FQ9ZS6
More data for this
Ligand-Target Pair