BDBM50240386 5-amino-4-oxopentanoic acid::5-aminolevulinic acid::AMINOLEVULINIC ACID::Aminolevulinic Acid Hydrochloride::CHEMBL601::Levulan::delta-aminolevulinic acid

SMILES: NCC(=O)CCC(O)=O

InChI Key: InChIKey=ZGXJTSGNIOSYLO-UHFFFAOYSA-N

Data: 4 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50240386   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oligopeptide transporter, kidney isoform (Rattus norvegicus)	BDBM50240386 (5-amino-4-oxopentanoic acid | 5-aminolevulinic aci...) Show SMILES NCC(=O)CCC(O)=O Show InChI InChI=1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Hospital Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells				Pflugers Arch 440: 679-84 (2000) Article DOI: 10.1007/s004240000339 BindingDB Entry DOI: 10.7270/Q2CR5X6C
					More data for this Ligand-Target Pair
Oligopeptide transporter small intestine isoform (Homo sapiens (Human))	BDBM50240386 (5-amino-4-oxopentanoic acid | 5-aminolevulinic aci...) Show SMILES NCC(=O)CCC(O)=O Show InChI InChI=1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	7.90E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition constant (Ki) for human intestinal peptide carrier				J Med Chem 46: 5725-34 (2003) Article DOI: 10.1021/jm030976x BindingDB Entry DOI: 10.7270/Q22N531C
					More data for this Ligand-Target Pair
Xaa-Pro dipeptidase (Homo sapiens (Human))	BDBM50240386 (5-amino-4-oxopentanoic acid | 5-aminolevulinic aci...) Show SMILES NCC(=O)CCC(O)=O Show InChI InChI=1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article	9.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against porcine kidney prolidase				Bioorg Med Chem Lett 5: 2825-2828 (1995) Article DOI: 10.1016/0960-894X(95)00494-E BindingDB Entry DOI: 10.7270/Q2JM29KW
					More data for this Ligand-Target Pair
Solute carrier family 15 member 1 (Rattus norvegicus)	BDBM50240386 (5-amino-4-oxopentanoic acid | 5-aminolevulinic aci...) Show SMILES NCC(=O)CCC(O)=O Show InChI InChI=1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.20E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto University Hospital Curated by ChEMBL					Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cells				Pflugers Arch 440: 679-84 (2000) Article DOI: 10.1007/s004240000339 BindingDB Entry DOI: 10.7270/Q2CR5X6C
					More data for this Ligand-Target Pair
GABA-C receptor (Homo sapiens (Human))	BDBM50240386 (5-amino-4-oxopentanoic acid | 5-aminolevulinic aci...) Show SMILES NCC(=O)CCC(O)=O Show InChI InChI=1S/C5H9NO3/c6-3-4(7)1-2-5(8)9/h1-3,6H2,(H,8,9)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clam...				J Med Chem 51: 3825-40 (2008) Article DOI: 10.1021/jm7015842 BindingDB Entry DOI: 10.7270/Q27M07RR
					More data for this Ligand-Target Pair