BDBM50240539 CHEMBL4103428

SMILES: Fc1cc(Cl)ccc1Oc1cc(ncn1)N1CCC(CC1)C(=O)N1CCc2ccccc2C1

InChI Key: InChIKey=PHSVYUSBYGMFRL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50240539 (CHEMBL4103428) Show SMILES Fc1cc(Cl)ccc1Oc1cc(ncn1)N1CCC(CC1)C(=O)N1CCc2ccccc2C1 Show InChI InChI=1S/C25H24ClFN4O2/c26-20-5-6-22(21(27)13-20)33-24-14-23(28-16-29-24)30-10-8-18(9-11-30)25(32)31-12-7-17-3-1-2-4-19(17)15-31/h1-6,13-14,16,18H,7-12,15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Antagonist activity at recombinant human M4 receptor expressed in CHO cells co-expressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 27: 2479-2483 (2017) Article DOI: 10.1016/j.bmcl.2017.04.009 BindingDB Entry DOI: 10.7270/Q2VT1V7H
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50240539 (CHEMBL4103428) Show SMILES Fc1cc(Cl)ccc1Oc1cc(ncn1)N1CCC(CC1)C(=O)N1CCc2ccccc2C1 Show InChI InChI=1S/C25H24ClFN4O2/c26-20-5-6-22(21(27)13-20)33-24-14-23(28-16-29-24)30-10-8-18(9-11-30)25(32)31-12-7-17-3-1-2-4-19(17)15-31/h1-6,13-14,16,18H,7-12,15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Antagonist activity at recombinant human M4 receptor expressed in CHO cells co-expressing Gqi5 by calcium mobilization assay				Bioorg Med Chem Lett 27: 2479-2483 (2017) Article DOI: 10.1016/j.bmcl.2017.04.009 BindingDB Entry DOI: 10.7270/Q2VT1V7H
					More data for this Ligand-Target Pair