BDBM50240669 Acetic acid (S)-5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl ester::CHEMBL87992::ESLICARBAZEPINE

SMILES: CC(=O)O[C@H]1Cc2ccccc2N(C(N)=O)c2ccccc12

InChI Key: InChIKey=QIALRBLEEWJACW-INIZCTEOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type I I alpha subunit (Rattus norvegicus)	BDBM50240669 (Acetic acid (S)-5-carbamoyl-10,11-dihydro-5H-diben...) Show SMILES CC(=O)O[C@H]1Cc2ccccc2N(C(N)=O)c2ccccc12 Show InChI InChI=1S/C17H16N2O3/c1-11(20)22-16-10-12-6-2-4-8-14(12)19(17(18)21)15-9-5-3-7-13(15)16/h2-9,16H,10H2,1H3,(H2,18,21)/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
BIAL Curated by ChEMBL					Assay Description Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomes				J Med Chem 42: 2582-7 (1999) Article DOI: 10.1021/jm980627g BindingDB Entry DOI: 10.7270/Q2QN69GZ
					More data for this Ligand-Target Pair
P2X purinoceptor 4 (Homo sapiens (Human))	BDBM50240669 (Acetic acid (S)-5-carbamoyl-10,11-dihydro-5H-diben...) Show SMILES CC(=O)O[C@H]1Cc2ccccc2N(C(N)=O)c2ccccc12 Show InChI InChI=1S/C17H16N2O3/c1-11(20)22-16-10-12-6-2-4-8-14(12)19(17(18)21)15-9-5-3-7-13(15)16/h2-9,16H,10H2,1H3,(H2,18,21)/t16-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubate...				Bioorg Med Chem 22: 1077-88 (2014) Article DOI: 10.1016/j.bmc.2013.12.035 BindingDB Entry DOI: 10.7270/Q21R6S09
					More data for this Ligand-Target Pair