Found 4 hits for monomerid = 50240800 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Fibroblast growth factor receptor 3
(Homo sapiens (Human)) | BDBM50240800
(CHEMBL4074407)Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(F)c(F)cc1O |r| Show InChI InChI=1S/C27H22F2N4O2/c1-15-19-9-17(7-8-24(19)33-32-15)20-10-18(31-25(14-34)16-5-3-2-4-6-16)13-30-27(20)21-11-22(28)23(29)12-26(21)35/h2-13,25,31,34-35H,14H2,1H3,(H,32,33)/t25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
J Med Chem 60: 6018-6035 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00076
BindingDB Entry DOI: 10.7270/Q2K939NC |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50240800
(CHEMBL4074407)Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(F)c(F)cc1O |r| Show InChI InChI=1S/C27H22F2N4O2/c1-15-19-9-17(7-8-24(19)33-32-15)20-10-18(31-25(14-34)16-5-3-2-4-6-16)13-30-27(20)21-11-22(28)23(29)12-26(21)35/h2-13,25,31,34-35H,14H2,1H3,(H,32,33)/t25-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 289 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of FGFR2 in human SNU16 cells assessed as inhibition of cell proliferation after 72 hrs by cell counting kit-8 assay |
J Med Chem 60: 6018-6035 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00076
BindingDB Entry DOI: 10.7270/Q2K939NC |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Homo sapiens (Human)) | BDBM50240800
(CHEMBL4074407)Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(F)c(F)cc1O |r| Show InChI InChI=1S/C27H22F2N4O2/c1-15-19-9-17(7-8-24(19)33-32-15)20-10-18(31-25(14-34)16-5-3-2-4-6-16)13-30-27(20)21-11-22(28)23(29)12-26(21)35/h2-13,25,31,34-35H,14H2,1H3,(H,32,33)/t25-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
In vitro inhibition of HMG-CoA reductase in solubilized rat liver. |
J Med Chem 60: 6018-6035 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00076
BindingDB Entry DOI: 10.7270/Q2K939NC |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM50240800
(CHEMBL4074407)Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(N[C@@H](CO)c2ccccc2)cnc1-c1cc(F)c(F)cc1O |r| Show InChI InChI=1S/C27H22F2N4O2/c1-15-19-9-17(7-8-24(19)33-32-15)20-10-18(31-25(14-34)16-5-3-2-4-6-16)13-30-27(20)21-11-22(28)23(29)12-26(21)35/h2-13,25,31,34-35H,14H2,1H3,(H,32,33)/t25-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISA |
J Med Chem 60: 6018-6035 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00076
BindingDB Entry DOI: 10.7270/Q2K939NC |
More data for this
Ligand-Target Pair | |
Search and Browse
