BDBM50240980 CHEMBL372450::N-(3-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)phenyl)-2,3'-bithiophene-5-carboxamide::[2,3']Bithiophenyl-5-carboxylic acid [3-(4-oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phenyl]-amide

SMILES: O=C(Nc1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)c1ccc(s1)-c1ccsc1

InChI Key: InChIKey=MFMIZBCYOYSYCP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240980   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50240980 (CHEMBL372450 | N-(3-((4-oxo-3,4-dihydrophthalazin-...) Show SMILES O=C(Nc1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)c1ccc(s1)-c1ccsc1 Show InChI InChI=1S/C24H17N3O2S2/c28-23-19-7-2-1-6-18(19)20(26-27-23)13-15-4-3-5-17(12-15)25-24(29)22-9-8-21(31-22)16-10-11-30-14-16/h1-12,14H,13H2,(H,25,29)(H,27,28)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant PARP1				J Med Chem 52: 718-25 (2009) Article DOI: 10.1021/jm800902t BindingDB Entry DOI: 10.7270/Q2C53KPW
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50240980 (CHEMBL372450 | N-(3-((4-oxo-3,4-dihydrophthalazin-...) Show SMILES O=C(Nc1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)c1ccc(s1)-c1ccsc1 Show InChI InChI=1S/C24H17N3O2S2/c28-23-19-7-2-1-6-18(19)20(26-27-23)13-15-4-3-5-17(12-15)25-24(29)22-9-8-21(31-22)16-10-11-30-14-16/h1-12,14H,13H2,(H,25,29)(H,27,28)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
KuDOS Horsham Ltd Curated by ChEMBL					Assay Description Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)				Bioorg Med Chem Lett 15: 2235-8 (2005) Article DOI: 10.1016/j.bmcl.2005.03.026 BindingDB Entry DOI: 10.7270/Q2QV3M0B
					More data for this Ligand-Target Pair