BDBM50241006 3-(2-aminoethyl)-2-chloro-4-hydroxy-5-phenylthieno[2,3-b]pyridin-6(7H)-one::CHEMBL380963

SMILES: NCCc1c(Cl)sc2[nH]c(=O)c(-c3ccccc3)c(O)c12

InChI Key: InChIKey=NFCXBOFCIPCUSM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50241006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50241006 (3-(2-aminoethyl)-2-chloro-4-hydroxy-5-phenylthieno...) Show SMILES NCCc1c(Cl)sc2[nH]c(=O)c(-c3ccccc3)c(O)c12 Show InChI InChI=1S/C15H13ClN2O2S/c16-13-9(6-7-17)11-12(19)10(8-4-2-1-3-5-8)14(20)18-15(11)21-13/h1-5H,6-7,17H2,(H2,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [3H]raclopride from dopamine receptor D2 in rat striatal membrane				J Med Chem 49: 864-71 (2006) Article DOI: 10.1021/jm0503493 BindingDB Entry DOI: 10.7270/Q2513XS4
					More data for this Ligand-Target Pair