BDBM50241023 CHEMBL4103149

SMILES: NC(=O)c1ccc2COc3cc(Nc4cc(NC(=O)c5cccs5)c(F)cc4F)ccc3C(=O)c2c1

InChI Key: InChIKey=KMHDTKSZCYYVDR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241023 (CHEMBL4103149) Show SMILES NC(=O)c1ccc2COc3cc(Nc4cc(NC(=O)c5cccs5)c(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C26H17F2N3O4S/c27-18-10-19(28)21(31-26(34)23-2-1-7-36-23)11-20(18)30-15-5-6-16-22(9-15)35-12-14-4-3-13(25(29)33)8-17(14)24(16)32/h1-11,30H,12H2,(H2,29,33)(H,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universitaet Tuebingen Curated by ChEMBL					Assay Description Inhibition of P38 alpha MAPK in human whole blood assessed as reduction in TNF-alpha release after 10 mins by ELISA				J Med Chem 60: 8027-8054 (2017) Article DOI: 10.1021/acs.jmedchem.7b00745 BindingDB Entry DOI: 10.7270/Q2RV0QVZ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50241023 (CHEMBL4103149) Show SMILES NC(=O)c1ccc2COc3cc(Nc4cc(NC(=O)c5cccs5)c(F)cc4F)ccc3C(=O)c2c1 Show InChI InChI=1S/C26H17F2N3O4S/c27-18-10-19(28)21(31-26(34)23-2-1-7-36-23)11-20(18)30-15-5-6-16-22(9-15)35-12-14-4-3-13(25(29)33)8-17(14)24(16)32/h1-11,30H,12H2,(H2,29,33)(H,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universitaet Tuebingen Curated by ChEMBL					Assay Description Displacement of [3H]DSLET from delta opioid receptor in rat brain membrane				J Med Chem 60: 8027-8054 (2017) Article DOI: 10.1021/acs.jmedchem.7b00745 BindingDB Entry DOI: 10.7270/Q2RV0QVZ
					More data for this Ligand-Target Pair