BDBM50241177 (R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-yl)-N,N-dimethyl-1,2,4-oxadiazole-3-carboxamide::5-{(1R)-4-cyclohexyl-1-[2-(hydroxylamino)-2-oxoethyl]butyl}-1,2,4-oxadiazole-3-carboxamide::CHEMBL226686

SMILES: CN(C)C(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO

InChI Key: InChIKey=FRASWKFJOBLAQF-CYBMUJFWSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50241177   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50241177 ((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...) Show SMILES CN(C)C(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO |r| Show InChI InChI=1S/C17H28N4O4/c1-21(2)17(23)15-18-16(25-20-15)13(11-14(22)19-24)10-6-9-12-7-4-3-5-8-12/h12-13,24H,3-11H2,1-2H3,(H,19,22)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human procollagen C-proteinase expressed in CHO cells by fluorescence assay				Bioorg Med Chem Lett 18: 6562-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.036 BindingDB Entry DOI: 10.7270/Q2J1031M
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50241177 ((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...) Show SMILES CN(C)C(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO |r| Show InChI InChI=1S/C17H28N4O4/c1-21(2)17(23)15-18-16(25-20-15)13(11-14(22)19-24)10-6-9-12-7-4-3-5-8-12/h12-13,24H,3-11H2,1-2H3,(H,19,22)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human MMP3 by fluorescence assay				Bioorg Med Chem Lett 18: 6562-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.036 BindingDB Entry DOI: 10.7270/Q2J1031M
					More data for this Ligand-Target Pair
Bone morphogenetic protein 1 (Homo sapiens (Human))	BDBM50241177 ((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...) Show SMILES CN(C)C(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO |r| Show InChI InChI=1S/C17H28N4O4/c1-21(2)17(23)15-18-16(25-20-15)13(11-14(22)19-24)10-6-9-12-7-4-3-5-8-12/h12-13,24H,3-11H2,1-2H3,(H,19,22)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation counting				Bioorg Med Chem Lett 18: 6562-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.036 BindingDB Entry DOI: 10.7270/Q2J1031M
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50241177 ((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...) Show SMILES CN(C)C(=O)c1noc(n1)[C@H](CCCC1CCCCC1)CC(=O)NO |r| Show InChI InChI=1S/C17H28N4O4/c1-21(2)17(23)15-18-16(25-20-15)13(11-14(22)19-24)10-6-9-12-7-4-3-5-8-12/h12-13,24H,3-11H2,1-2H3,(H,19,22)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human MMP2 by fluorescence assay				Bioorg Med Chem Lett 18: 6562-7 (2008) Article DOI: 10.1016/j.bmcl.2008.10.036 BindingDB Entry DOI: 10.7270/Q2J1031M
					More data for this Ligand-Target Pair