BDBM50241351 5-Amino-2-methyl-4-pyridin-4-yl-6,7,8,9-tetrahydro-benzo[b][1,8]naphthyridine-3-carboxylic acid ethyl ester::CHEMBL253783::ethyl 5-amino-2-methyl-4-(pyridin-4-yl)-6,7,8,9-tetrahydrobenzo[b][1,8]naphthyridine-3-carboxylate

SMILES: CCOC(=O)c1c(C)nc2nc3CCCCc3c(N)c2c1-c1ccncc1

InChI Key: InChIKey=CHKXZOMLVXBARM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM50241351 (5-Amino-2-methyl-4-pyridin-4-yl-6,7,8,9-tetrahydro...) Show SMILES CCOC(=O)c1c(C)nc2nc3CCCCc3c(N)c2c1-c1ccncc1 Show InChI InChI=1S/C21H22N4O2/c1-3-27-21(26)16-12(2)24-20-18(17(16)13-8-10-23-11-9-13)19(22)14-6-4-5-7-15(14)25-20/h8-11H,3-7H2,1-2H3,(H2,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AChE (unknown origin) using acetylthiocholine chloride as substrate after 15 min by Ellman's method				Citation and Details Article DOI: 10.1007/s00044-010-9516-x BindingDB Entry DOI: 10.7270/Q2R78J3V
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50241351 (5-Amino-2-methyl-4-pyridin-4-yl-6,7,8,9-tetrahydro...) Show SMILES CCOC(=O)c1c(C)nc2nc3CCCCc3c(N)c2c1-c1ccncc1 Show InChI InChI=1S/C21H22N4O2/c1-3-27-21(26)16-12(2)24-20-18(17(16)13-8-10-23-11-9-13)19(22)14-6-4-5-7-15(14)25-20/h8-11H,3-7H2,1-2H3,(H2,22,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIC) Curated by ChEMBL					Assay Description Inhibition of Electrophorus electricus AChE by spectrophotometry				Bioorg Med Chem 16: 7759-69 (2008) Article DOI: 10.1016/j.bmc.2008.07.005 BindingDB Entry DOI: 10.7270/Q2DZ096D
					More data for this Ligand-Target Pair