BDBM50241483 CHEMBL4101228

SMILES: Nc1ccccc1NC(=O)c1ccc(NC(=S)NCc2ccc3OCOc3c2)cc1

InChI Key: InChIKey=MDFBVGXNRBSHEJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50241483 (CHEMBL4101228) Show SMILES Nc1ccccc1NC(=O)c1ccc(NC(=S)NCc2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C22H20N4O3S/c23-17-3-1-2-4-18(17)26-21(27)15-6-8-16(9-7-15)25-22(30)24-12-14-5-10-19-20(11-14)29-13-28-19/h1-11H,12-13,23H2,(H,26,27)(H2,24,25,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of human recombinant NAMPT using NAM as substrate preincubated for 5 mins followed by substrate addition measured after 15 mins by fluores...				J Med Chem 60: 7965-7983 (2017) Article DOI: 10.1021/acs.jmedchem.7b00467 BindingDB Entry DOI: 10.7270/Q2VM4FDV
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50241483 (CHEMBL4101228) Show SMILES Nc1ccccc1NC(=O)c1ccc(NC(=S)NCc2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C22H20N4O3S/c23-17-3-1-2-4-18(17)26-21(27)15-6-8-16(9-7-15)25-22(30)24-12-14-5-10-19-20(11-14)29-13-28-19/h1-11H,12-13,23H2,(H,26,27)(H2,24,25,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 (1 to 482 residues) expressed in Baculovirus using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 5 mins ...				J Med Chem 60: 7965-7983 (2017) Article DOI: 10.1021/acs.jmedchem.7b00467 BindingDB Entry DOI: 10.7270/Q2VM4FDV
					More data for this Ligand-Target Pair