BDBM50241485 CHEMBL4060041
SMILES: [H][C@]12O[C@@]3(Cc4ccccc4)O[C@]1(C[C@@H](C)[C@]1(O3)[C@]3([H])C=C(C)C(=O)[C@@]3(O)CC(COC(=O)Cc3ccc(O)c(OC)c3)=C[C@]21[H])C(C)=C
InChI Key: InChIKey=DSDNAKHZNJAGHN-LHYNMVLISA-N
Data: 2 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50241485 (CHEMBL4060041) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Binding affinity to human TRPV1 expressed in CHO cells after 45 mins by scintillation counting method | J Med Chem 60: 8246-8252 (2017) Article DOI: 10.1021/acs.jmedchem.7b00859 BindingDB Entry DOI: 10.7270/Q2QV3PNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vanilloid receptor (Rattus norvegicus (rat)) | BDBM50241485 (CHEMBL4060041) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.0640 | n/a | n/a | n/a | n/a | n/a |
National Cancer Institute Curated by ChEMBL | Assay Description Binding affinity to rat TRPV1 after 45 mins by scintillation counting method | J Med Chem 60: 8246-8252 (2017) Article DOI: 10.1021/acs.jmedchem.7b00859 BindingDB Entry DOI: 10.7270/Q2QV3PNP | |||||||||||
More data for this Ligand-Target Pair |