BDBM50241633 CHEMBL4095486
SMILES: N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1c1nc(c[nH]1)-c1ccccc1
InChI Key: InChIKey=XNWVPLWFFIGCKG-DHGKCCLASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit)) | BDBM50241633 (CHEMBL4095486) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 2.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Debrecen Curated by ChEMBL | Assay Description The compound was tested for the inhibition of fibrinogen receptor | J Med Chem 60: 9251-9262 (2017) Article DOI: 10.1021/acs.jmedchem.7b01056 BindingDB Entry DOI: 10.7270/Q2ZC851N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Liver glycogen phosphorylase (Homo sapiens (Human)) | BDBM50241633 (CHEMBL4095486) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 2.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Debrecen Curated by ChEMBL | Assay Description Competitive inhibition of 6xHis-tagged human liver glycogen phosphorylase-a expressed in Escherichia coli BL21 Gold (DE3) assessed as release of inor... | J Med Chem 60: 9251-9262 (2017) Article DOI: 10.1021/acs.jmedchem.7b01056 BindingDB Entry DOI: 10.7270/Q2ZC851N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen phosphorylase, muscle form (Oryctolagus cuniculus (rabbit)) | BDBM50241633 (CHEMBL4095486) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 3.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Debrecen Curated by ChEMBL | Assay Description Competitive inhibition of rabbit muscle glycogen phosphorylase-a in presence of varying levels of glucose-1-phosphate and constant concentration of g... | J Med Chem 60: 9251-9262 (2017) Article DOI: 10.1021/acs.jmedchem.7b01056 BindingDB Entry DOI: 10.7270/Q2ZC851N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |