BDBM50241865 2,5-dideoxy-2,5-imino-D-altritol::2R,5R-dihydroxymethyl-3R,4R-dihydroxypyrrolidine::CHEMBL469844

SMILES: OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O

InChI Key: InChIKey=PFYHYHZGDNWFIF-KAZBKCHUSA-N

Data: 2 KI  10 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50241865   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie der Technischen Universität Graz Curated by ChEMBL					Assay Description Inhibitory activity against Agrobacterium sp. Beta-glucosidase employing fluorescence spectrometric method				Bioorg Med Chem Lett 11: 1339-42 (2001) BindingDB Entry DOI: 10.7270/Q2JQ1097
					More data for this Ligand-Target Pair
Alpha-glucosidase A (α-Gal A) (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Competitive inhibition of human lysosome alpha-galactosidase by Lineweaver-Burk plot analysis				Bioorg Med Chem 18: 3790-4 (2010) Article DOI: 10.1016/j.bmc.2010.04.048 BindingDB Entry DOI: 10.7270/Q2XK8FQP
					More data for this Ligand-Target Pair
α-galactosidase (Coffea arabica (Coffee beans))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	6.5	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of coffee bean alpha-galactosidase assessed as p-nitrophenol release at pH 6.5 by spectrometric analysis				Bioorg Med Chem 18: 3790-4 (2010) Article DOI: 10.1016/j.bmc.2010.04.048 BindingDB Entry DOI: 10.7270/Q2XK8FQP
					More data for this Ligand-Target Pair
Alpha-glucosidase A (α-Gal A) (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of human lysosome alpha-galactosidase assessed as p-nitrophenol release by spectrometric analysis				Bioorg Med Chem 18: 3790-4 (2010) Article DOI: 10.1016/j.bmc.2010.04.048 BindingDB Entry DOI: 10.7270/Q2XK8FQP
					More data for this Ligand-Target Pair
Lactase-glycosylceramidase (Rattus norvegicus)	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of rat intestinal lactase assessed as p-nitrophenol release by spectrometric analysis				Bioorg Med Chem 18: 3790-4 (2010) Article DOI: 10.1016/j.bmc.2010.04.048 BindingDB Entry DOI: 10.7270/Q2XK8FQP
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 4.6 after 15 mins by fluorescence...				Eur J Med Chem 126: 1-6 (2017) BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	7.0	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...				Eur J Med Chem 123: 14-20 (2016) Article DOI: 10.1016/j.ejmech.2016.07.025 BindingDB Entry DOI: 10.7270/Q2RB76KN
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	4.6	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 4.6 after 10 mins by fluore...				Eur J Med Chem 123: 14-20 (2016) Article DOI: 10.1016/j.ejmech.2016.07.025 BindingDB Entry DOI: 10.7270/Q2RB76KN
					More data for this Ligand-Target Pair
Alpha-galactosidase A (Homo sapiens (Human))	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
National Cheng-Kung University Curated by ChEMBL					Assay Description Inhibition of recombinant human alpha GAL-A using 4-methylumbelliferyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluorescence a...				Eur J Med Chem 126: 1-6 (2017) BindingDB Entry DOI: 10.7270/Q2KP84DV
					More data for this Ligand-Target Pair
Beta-glucosidase A (Caldocellum saccharolyticum)	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	5.0	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of Caldocellum saccharolyticum beta-glucosidase assessed as p-nitrophenol release at pH 5 by spectrometric analysis				Bioorg Med Chem 18: 3790-4 (2010) Article DOI: 10.1016/j.bmc.2010.04.048 BindingDB Entry DOI: 10.7270/Q2XK8FQP
					More data for this Ligand-Target Pair
Probable alpha-glucosidase Os06g0675700 (Oryza sativa subsp. japonica)	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.71E+5	n/a	n/a	n/a	n/a	5.0	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of rice alpha-glucosidase assessed as D-glucose release at pH 5 after 10 to 30 mins				Bioorg Med Chem 18: 3790-4 (2010) Article DOI: 10.1016/j.bmc.2010.04.048 BindingDB Entry DOI: 10.7270/Q2XK8FQP
					More data for this Ligand-Target Pair
Alpha-L-fucosidase 1 (Bos taurus)	BDBM50241865 (2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...) Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H13NO4/c8-1-3-5(10)6(11)4(2-9)7-3/h3-11H,1-2H2/t3-,4-,5-,6+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.03E+5	n/a	n/a	n/a	n/a	5.5	n/a
University of Toyama Curated by ChEMBL					Assay Description Inhibition of bovine epididymis alpha-L-fucosidase assessed as p-nitrophenol release at pH 5.5 by spectrometric analysis				Bioorg Med Chem 18: 3790-4 (2010) Article DOI: 10.1016/j.bmc.2010.04.048 BindingDB Entry DOI: 10.7270/Q2XK8FQP
					More data for this Ligand-Target Pair