BindingDB PrimarySearch

BDBM50241984 BASTADIN 6::CHEMBL505907::bastadin-6

SMILES: Oc1c(Br)cc2CCNC(=O)C(Cc3cc(Br)c(Oc4cc(CC(N=O)C(=O)NCCc5cc(Br)c(Oc1c2)c(Br)c5)cc(Br)c4O)c(Br)c3)N=O

InChI Key: InChIKey=GDQQKBZRPYUTRS-UHFFFAOYSA-N

Data: 7 IC50 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50241984
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ryanodine receptor 1 (Homo sapiens (Human))	BDBM50241984 (BASTADIN 6 \| CHEMBL505907 \| bastadin-6) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Displacement of [3H]ryanodine from RyR1 calcium channel in sarcoplasmic reticulum assessed as calcium mobilization				J Nat Prod 66: 112-4 (2003) Article DOI: 10.1021/np020382h BindingDB Entry DOI: 10.7270/Q2HM587T
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-Dependent Kinase 4 (CDK4) (Homo sapiens (Human))	BDBM50241984 (BASTADIN 6 \| CHEMBL505907 \| bastadin-6) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine University Curated by ChEMBL					Assay Description Inhibition of CDK4/cyclin-D1 (unknown origin)				J Nat Prod 76: 121-5 (2013) Article DOI: 10.1021/np300764u BindingDB Entry DOI: 10.7270/Q21N82F5
Heinrich-Heine University Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50241984 (BASTADIN 6 \| CHEMBL505907 \| bastadin-6) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine University Curated by ChEMBL					Assay Description Inhibition of aurora-B (unknown origin)				J Nat Prod 76: 121-5 (2013) Article DOI: 10.1021/np300764u BindingDB Entry DOI: 10.7270/Q21N82F5
Heinrich-Heine University Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50241984 (BASTADIN 6 \| CHEMBL505907 \| bastadin-6) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine University Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin)				J Nat Prod 76: 121-5 (2013) Article DOI: 10.1021/np300764u BindingDB Entry DOI: 10.7270/Q21N82F5
Heinrich-Heine University Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 8 (Homo sapiens (Human))	BDBM50241984 (BASTADIN 6 \| CHEMBL505907 \| bastadin-6) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine University Curated by ChEMBL					Assay Description Inhibition of COT (unknown origin)				J Nat Prod 76: 121-5 (2013) Article DOI: 10.1021/np300764u BindingDB Entry DOI: 10.7270/Q21N82F5
Heinrich-Heine University Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50241984 (BASTADIN 6 \| CHEMBL505907 \| bastadin-6) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine University Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin)				J Nat Prod 76: 121-5 (2013) Article DOI: 10.1021/np300764u BindingDB Entry DOI: 10.7270/Q21N82F5
Heinrich-Heine University Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50241984 (BASTADIN 6 \| CHEMBL505907 \| bastadin-6) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine University Curated by ChEMBL					Assay Description Inhibition of ERBB2 (unknown origin)				J Nat Prod 76: 121-5 (2013) Article DOI: 10.1021/np300764u BindingDB Entry DOI: 10.7270/Q21N82F5
Heinrich-Heine University Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50241984 (BASTADIN 6 \| CHEMBL505907 \| bastadin-6) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich-Heine University Curated by ChEMBL					Assay Description Inhibition of aurora-A (unknown origin)				J Nat Prod 76: 121-5 (2013) Article DOI: 10.1021/np300764u BindingDB Entry DOI: 10.7270/Q21N82F5
Heinrich-Heine University Curated by ChEMBL					More data for this Ligand-Target Pair