BDBM50242161 CHEMBL4097771

SMILES: CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cccnc3)cc2F)CC1

InChI Key: InChIKey=LWCQXJGSVJHFRS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242161   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50242161 (CHEMBL4097771) Show SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cccnc3)cc2F)CC1 Show InChI InChI=1S/C27H27FN4O/c1-20-5-7-23(16-22(20)8-6-21-4-3-11-29-18-21)27(33)30-25-10-9-24(26(28)17-25)19-32-14-12-31(2)13-15-32/h3-5,7,9-11,16-18H,12-15,19H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TU Dortmund University Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase				J Med Chem 60: 8801-8815 (2017) Article DOI: 10.1021/acs.jmedchem.7b00841 BindingDB Entry DOI: 10.7270/Q2VM4FN0
					More data for this Ligand-Target Pair