BDBM50242197 CHEMBL4102489

SMILES: OC(=O)CCc1nc2ccccc2nc1Sc1ccccc1

InChI Key: InChIKey=NKDPRFGARPEMMN-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50242197 (CHEMBL4102489) Show SMILES OC(=O)CCc1nc2ccccc2nc1Sc1ccccc1 Show InChI InChI=1S/C17H14N2O2S/c20-16(21)11-10-15-17(22-12-6-2-1-3-7-12)19-14-9-5-4-8-13(14)18-15/h1-9H,10-11H2,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
EntreMed Inc. Curated by ChEMBL					Assay Description Displacement of FITC-labeled RLRGG peptide from N-terminal His6-tagged HDAC6 zinc-finger ubiquitin binding domain (1109 to 1215 residues)(unknown ori...				J Med Chem 60: 9090-9096 (2017) Article DOI: 10.1021/acs.jmedchem.7b00933 BindingDB Entry DOI: 10.7270/Q2M32Z5T
					More data for this Ligand-Target Pair