BDBM50242379 CHEMBL4089659

SMILES: C(c1ccc2ccccc2c1)n1cnc2c(ncnc12)N1CCOCC1

InChI Key: InChIKey=GTFGFPRNMDUSAC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50242379 (CHEMBL4089659) Show SMILES C(c1ccc2ccccc2c1)n1cnc2c(ncnc12)N1CCOCC1 Show InChI InChI=1S/C20H19N5O/c1-2-4-17-11-15(5-6-16(17)3-1)12-25-14-23-18-19(21-13-22-20(18)25)24-7-9-26-10-8-24/h1-6,11,13-14H,7-10,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Nanchang University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDE10A1 (2 to 789 residues) expressed in baculovirus infected Sf9 cells using fluorescein-label...				Bioorg Med Chem 25: 3315-3329 (2017) Article DOI: 10.1016/j.bmc.2017.04.019 BindingDB Entry DOI: 10.7270/Q25X2CB8
					More data for this Ligand-Target Pair