BDBM50242383 CHEMBL4068257

SMILES: COc1ccc(cc1)-c1ccc(Cn2c(C)nc3c(ncnc23)N2CCOCC2)cc1

InChI Key: InChIKey=REKJIJAPMQSCJI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50242383 (CHEMBL4068257) Show SMILES COc1ccc(cc1)-c1ccc(Cn2c(C)nc3c(ncnc23)N2CCOCC2)cc1 Show InChI InChI=1S/C24H25N5O2/c1-17-27-22-23(28-11-13-31-14-12-28)25-16-26-24(22)29(17)15-18-3-5-19(6-4-18)20-7-9-21(30-2)10-8-20/h3-10,16H,11-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Nanchang University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDE10A1 (2 to 789 residues) expressed in baculovirus infected Sf9 cells using fluorescein-label...				Bioorg Med Chem 25: 3315-3329 (2017) Article DOI: 10.1016/j.bmc.2017.04.019 BindingDB Entry DOI: 10.7270/Q25X2CB8
					More data for this Ligand-Target Pair