BDBM50242387 CHEMBL4066336

SMILES: Cc1nc2c(ncnc2n1Cc1ccc(cc1)-c1cccnc1)N1CCOCC1

InChI Key: InChIKey=UKURLXUMKRHNLL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242387   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50242387 (CHEMBL4066336) Show SMILES Cc1nc2c(ncnc2n1Cc1ccc(cc1)-c1cccnc1)N1CCOCC1 Show InChI InChI=1S/C22H22N6O/c1-16-26-20-21(27-9-11-29-12-10-27)24-15-25-22(20)28(16)14-17-4-6-18(7-5-17)19-3-2-8-23-13-19/h2-8,13,15H,9-12,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Nanchang University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged PDE10A1 (2 to 789 residues) expressed in baculovirus infected Sf9 cells using fluorescein-label...				Bioorg Med Chem 25: 3315-3329 (2017) Article DOI: 10.1016/j.bmc.2017.04.019 BindingDB Entry DOI: 10.7270/Q25X2CB8
					More data for this Ligand-Target Pair