BDBM50242474 (2S,4S)-1-{N-[2-(Diethylamino)-1,1-dimethylethyl]glycyl}-4-fluoropyrrolidine-2-carbonitrile::CHEMBL511128

SMILES: CCN(CC)CC(C)(C)NCC(=O)N1C[C@@H](F)C[C@H]1C#N

InChI Key: InChIKey=WRKOKRYWOZCHPP-STQMWFEESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50242474 ((2S,4S)-1-{N-[2-(Diethylamino)-1,1-dimethylethyl]g...) Show SMILES CCN(CC)CC(C)(C)NCC(=O)N1C[C@@H](F)C[C@H]1C#N |r| Show InChI InChI=1S/C15H27FN4O/c1-5-19(6-2)11-15(3,4)18-9-14(21)20-10-12(16)7-13(20)8-17/h12-13,18H,5-7,9-11H2,1-4H3/t12-,13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	252	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of DPP4 in human plasma by fluorescence assay				Bioorg Med Chem 16: 4093-106 (2008) Article DOI: 10.1016/j.bmc.2008.01.016 BindingDB Entry DOI: 10.7270/Q27H1KGN
					More data for this Ligand-Target Pair