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SMILES: O=c1oc2cc(ccc2n1Cc1cccc2CCNCc12)S(=O)(=O)Nc1ncns1

InChI Key: InChIKey=SGBRXFSGVCHLHG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242507   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM50242507
PNG
(CHEMBL4102898)
Show SMILES O=c1oc2cc(ccc2n1Cc1cccc2CCNCc12)S(=O)(=O)Nc1ncns1
Show InChI InChI=1S/C19H17N5O4S2/c25-19-24(10-13-3-1-2-12-6-7-20-9-15(12)13)16-5-4-14(8-17(16)28-19)30(26,27)23-18-21-11-22-29-18/h1-5,8,11,20H,6-7,9-10H2,(H,21,22,23)
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KEGG

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Similars
Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Merck& Co.

Curated by ChEMBL


Assay Description
Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...

Bioorg Med Chem Lett 27: 2683-2688 (2017)


Article DOI: 10.1016/j.bmcl.2017.04.040
BindingDB Entry DOI: 10.7270/Q2SN0CD7
More data for this
Ligand-Target Pair