BDBM50242524 CHEMBL4102074

SMILES: COc1ccccc1CNc1nc(N)nc2[nH]c3ccc(O)cc3c12

InChI Key: InChIKey=YPSPRZBLDKBSHL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242524   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50242524 (CHEMBL4102074) Show SMILES COc1ccccc1CNc1nc(N)nc2[nH]c3ccc(O)cc3c12 Show InChI InChI=1S/C18H17N5O2/c1-25-14-5-3-2-4-10(14)9-20-16-15-12-8-11(24)6-7-13(12)21-17(15)23-18(19)22-16/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting anal...				Bioorg Med Chem Lett 27: 2708-2712 (2017) Article DOI: 10.1016/j.bmcl.2017.04.053 BindingDB Entry DOI: 10.7270/Q2J67KBT
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50242524 (CHEMBL4102074) Show SMILES COc1ccccc1CNc1nc(N)nc2[nH]c3ccc(O)cc3c12 Show InChI InChI=1S/C18H17N5O2/c1-25-14-5-3-2-4-10(14)9-20-16-15-12-8-11(24)6-7-13(12)21-17(15)23-18(19)22-16/h2-8,24H,9H2,1H3,(H4,19,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using poly(Glu,Tyr)4:1 as substrate in presence of [gamma-33P]-ATP after 60 mins by scintillation counting analys...				Bioorg Med Chem Lett 27: 2708-2712 (2017) Article DOI: 10.1016/j.bmcl.2017.04.053 BindingDB Entry DOI: 10.7270/Q2J67KBT
					More data for this Ligand-Target Pair