BDBM50242556 4-((4-Chlorophenyl)(2,3-dichlorophenyl)methyl)-N-cyclohexylpiperazine-1-carboxamide::CHEMBL487853

SMILES: Clc1ccc(cc1)C(N1CCN(CC1)C(=O)NC1CCCCC1)c1cccc(Cl)c1Cl

InChI Key: InChIKey=BWRQQTYERKIARX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50242556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50242556 (4-((4-Chlorophenyl)(2,3-dichlorophenyl)methyl)-N-c...) Show SMILES Clc1ccc(cc1)C(N1CCN(CC1)C(=O)NC1CCCCC1)c1cccc(Cl)c1Cl Show InChI InChI=1S/C24H28Cl3N3O/c25-18-11-9-17(10-12-18)23(20-7-4-8-21(26)22(20)27)29-13-15-30(16-14-29)24(31)28-19-5-2-1-3-6-19/h4,7-12,19,23H,1-3,5-6,13-16H2,(H,28,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	441	n/a	n/a	n/a	n/a	n/a	n/a
Central Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human CB1 receptor expressed in CHOK1 cells by luciferase assay				Bioorg Med Chem 16: 4035-51 (2008) Article DOI: 10.1016/j.bmc.2008.01.023 BindingDB Entry DOI: 10.7270/Q2B56JH2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50242556 (4-((4-Chlorophenyl)(2,3-dichlorophenyl)methyl)-N-c...) Show SMILES Clc1ccc(cc1)C(N1CCN(CC1)C(=O)NC1CCCCC1)c1cccc(Cl)c1Cl Show InChI InChI=1S/C24H28Cl3N3O/c25-18-11-9-17(10-12-18)23(20-7-4-8-21(26)22(20)27)29-13-15-30(16-14-29)24(31)28-19-5-2-1-3-6-19/h4,7-12,19,23H,1-3,5-6,13-16H2,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
Central Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from CB1 receptor in Sprague-Dawley rat cerebella membrane				Bioorg Med Chem 16: 4035-51 (2008) Article DOI: 10.1016/j.bmc.2008.01.023 BindingDB Entry DOI: 10.7270/Q2B56JH2
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50242556 (4-((4-Chlorophenyl)(2,3-dichlorophenyl)methyl)-N-c...) Show SMILES Clc1ccc(cc1)C(N1CCN(CC1)C(=O)NC1CCCCC1)c1cccc(Cl)c1Cl Show InChI InChI=1S/C24H28Cl3N3O/c25-18-11-9-17(10-12-18)23(20-7-4-8-21(26)22(20)27)29-13-15-30(16-14-29)24(31)28-19-5-2-1-3-6-19/h4,7-12,19,23H,1-3,5-6,13-16H2,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]WIN55212-2 from human CB2 receptor expressed in CHOK1 cells				Bioorg Med Chem 16: 4035-51 (2008) Article DOI: 10.1016/j.bmc.2008.01.023 BindingDB Entry DOI: 10.7270/Q2B56JH2
					More data for this Ligand-Target Pair