null

SMILES: COc1ccc(cc1)N1CCN(CC1)C(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O

InChI Key: InChIKey=MMTOMJQNAPDMIU-KTKRTIGZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242625   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein mono-ADP-ribosyltransferase PARP14 (Homo sapiens (Human))	BDBM50242625 (CHEMBL4081650) Show SMILES COc1ccc(cc1)N1CCN(CC1)C(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O Show InChI InChI=1S/C22H24N4O4/c1-30-19-7-5-18(6-8-19)25-11-13-26(14-12-25)21(28)10-9-20(27)24-17-4-2-3-16(15-17)22(23)29/h2-10,15H,11-14H2,1H3,(H2,23,29)(H,24,27)/b10-9-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...				Bioorg Med Chem Lett 27: 2907-2911 (2017) Article DOI: 10.1016/j.bmcl.2017.04.089 BindingDB Entry DOI: 10.7270/Q24X5B5F
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP14 (Homo sapiens (Human))	BDBM50242625 (CHEMBL4081650) Show SMILES COc1ccc(cc1)N1CCN(CC1)C(=O)\C=C/C(=O)Nc1cccc(c1)C(N)=O Show InChI InChI=1S/C22H24N4O4/c1-30-19-7-5-18(6-8-19)25-11-13-26(14-12-25)21(28)10-9-20(27)24-17-4-2-3-16(15-17)22(23)29/h2-10,15H,11-14H2,1H3,(H2,23,29)(H,24,27)/b10-9-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...				Bioorg Med Chem Lett 27: 2907-2911 (2017) Article DOI: 10.1016/j.bmcl.2017.04.089 BindingDB Entry DOI: 10.7270/Q24X5B5F
					More data for this Ligand-Target Pair