BDBM50242663 CHEMBL4101188

SMILES: NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCC(CC2)c2ccccc2)c1

InChI Key: InChIKey=WDJAWISJNZICTM-KTKRTIGZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50242663 (CHEMBL4101188) Show SMILES NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCC(CC2)c2ccccc2)c1 Show InChI InChI=1S/C22H23N3O3/c23-22(28)18-7-4-8-19(15-18)24-20(26)9-10-21(27)25-13-11-17(12-14-25)16-5-2-1-3-6-16/h1-10,15,17H,11-14H2,(H2,23,28)(H,24,26)/b10-9-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...				Bioorg Med Chem Lett 27: 2907-2911 (2017) Article DOI: 10.1016/j.bmcl.2017.04.089 BindingDB Entry DOI: 10.7270/Q24X5B5F
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 14 (Homo sapiens (Human))	BDBM50242663 (CHEMBL4101188) Show SMILES NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCC(CC2)c2ccccc2)c1 Show InChI InChI=1S/C22H23N3O3/c23-22(28)18-7-4-8-19(15-18)24-20(26)9-10-21(27)25-13-11-17(12-14-25)16-5-2-1-3-6-16/h1-10,15,17H,11-14H2,(H2,23,28)(H,24,26)/b10-9-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
McDaniel College Curated by ChEMBL					Assay Description Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...				Bioorg Med Chem Lett 27: 2907-2911 (2017) Article DOI: 10.1016/j.bmcl.2017.04.089 BindingDB Entry DOI: 10.7270/Q24X5B5F
					More data for this Ligand-Target Pair