BDBM50242718 3-(4-(-3-(3-chloro-4-fluorophenyl)-3-oxoprop-1-enyl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide::CHEMBL461493

SMILES: Cn1cc(\C=C\C(=O)c2ccc(F)c(Cl)c2)cc1\C=C\C(=O)NO

InChI Key: InChIKey=REUKHKYCPQUSHC-DDEVBNQJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242718   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD1B (Zea mays)	BDBM50242718 (3-(4-(-3-(3-chloro-4-fluorophenyl)-3-oxoprop-1-eny...) Show SMILES Cn1cc(\C=C\C(=O)c2ccc(F)c(Cl)c2)cc1\C=C\C(=O)NO Show InChI InChI=1S/C17H14ClFN2O3/c1-21-10-11(8-13(21)4-7-17(23)20-24)2-6-16(22)12-3-5-15(19)14(18)9-12/h2-10,24H,1H3,(H,20,23)/b6-2+,7-4+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 1B				Eur J Med Chem 43: 621-32 (2008) Article DOI: 10.1016/j.ejmech.2007.05.004 BindingDB Entry DOI: 10.7270/Q28K78V4
					More data for this Ligand-Target Pair