BDBM50242724 3-(4-(3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-oxoprop-1-enyl)-1-methyl-1H-pyrrol-2-yl)-N-hydroxyacrylamide::CHEMBL516805

SMILES: Cn1cc(\C=C\C(=O)c2ccc3OCCOc3c2)cc1\C=C\C(=O)NO

InChI Key: InChIKey=USZQNGSQWHZMSE-XIIDOLPRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50242724   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD1B (Zea mays)	BDBM50242724 (3-(4-(3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-ox...) Show SMILES Cn1cc(\C=C\C(=O)c2ccc3OCCOc3c2)cc1\C=C\C(=O)NO Show InChI InChI=1S/C19H18N2O5/c1-21-12-13(10-15(21)4-7-19(23)20-24)2-5-16(22)14-3-6-17-18(11-14)26-9-8-25-17/h2-7,10-12,24H,8-9H2,1H3,(H,20,23)/b5-2+,7-4+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	621	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize histone deacetylase 1B				Eur J Med Chem 43: 621-32 (2008) Article DOI: 10.1016/j.ejmech.2007.05.004 BindingDB Entry DOI: 10.7270/Q28K78V4
					More data for this Ligand-Target Pair