BDBM50243008 CHEMBL469682::N,N-Diethyl-2-(2-(4-(3-fluoropropoxy)phenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide

SMILES: CCN(CC)C(=O)Cc1c(nn2c(C)cc(C)nc12)-c1ccc(OCCCF)cc1

InChI Key: InChIKey=MDSWWISMWYFQEL-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50243008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat))	BDBM50243008 (CHEMBL469682 | N,N-Diethyl-2-(2-(4-(3-fluoropropox...) Show SMILES CCN(CC)C(=O)Cc1c(nn2c(C)cc(C)nc12)-c1ccc(OCCCF)cc1 Show InChI InChI=1S/C23H29FN4O2/c1-5-27(6-2)21(29)15-20-22(26-28-17(4)14-16(3)25-23(20)28)18-8-10-19(11-9-18)30-13-7-12-24/h8-11,14H,5-7,12-13,15H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
France; Inserm/CEA/Universit£ Paris Sud Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from TSPO in rat heart membranes after 15 mins by scintillation counting method				Eur J Med Chem 125: 346-359 (2017) Article DOI: 10.1016/j.ejmech.2016.09.025 BindingDB Entry DOI: 10.7270/Q2TH8PVR
					More data for this Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat))	BDBM50243008 (CHEMBL469682 | N,N-Diethyl-2-(2-(4-(3-fluoropropox...) Show SMILES CCN(CC)C(=O)Cc1c(nn2c(C)cc(C)nc12)-c1ccc(OCCCF)cc1 Show InChI InChI=1S/C23H29FN4O2/c1-5-27(6-2)21(29)15-20-22(26-28-17(4)14-16(3)25-23(20)28)18-8-10-19(11-9-18)30-13-7-12-24/h8-11,14H,5-7,12-13,15H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Radiopharmaceuticals Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from peripheral benzodiazepine receptor in rat kidney membrane				J Med Chem 51: 3700-12 (2008) Article DOI: 10.1021/jm7014556 BindingDB Entry DOI: 10.7270/Q2Z037ZW
					More data for this Ligand-Target Pair
Peripheral-Type Benzodiazepine Receptor (Rattus norvegicus (rat))	BDBM50243008 (CHEMBL469682 | N,N-Diethyl-2-(2-(4-(3-fluoropropox...) Show SMILES CCN(CC)C(=O)Cc1c(nn2c(C)cc(C)nc12)-c1ccc(OCCCF)cc1 Show InChI InChI=1S/C23H29FN4O2/c1-5-27(6-2)21(29)15-20-22(26-28-17(4)14-16(3)25-23(20)28)18-8-10-19(11-9-18)30-13-7-12-24/h8-11,14H,5-7,12-13,15H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Radiopharmaceuticals Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]Ro 5-4864 from peripheral benzodiazepine receptor in rat kidney membrane				J Med Chem 51: 3700-12 (2008) Article DOI: 10.1021/jm7014556 BindingDB Entry DOI: 10.7270/Q2Z037ZW
					More data for this Ligand-Target Pair