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SMILES: C[C@@H]1CCCN1CCc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C(=O)c1cccnc1

InChI Key: InChIKey=QBVCFQVKWFEYCU-HFRGRHLUSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50243639   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Rattus norvegicus (rat))		BDBM50243639
PNG
(((3aR,6aR)-6-(4-(2-((R)-2-methylpyrrolidin-1-yl)et...)
Show SMILES C[C@@H]1CCCN1CCc1ccc(cc1)C1=CC[C@H]2CN(C[C@@H]12)C(=O)c1cccnc1 |r,t:16|
Show InChI InChI=1S/C26H31N3O/c1-19-4-3-14-28(19)15-12-20-6-8-21(9-7-20)24-11-10-23-17-29(18-25(23)24)26(30)22-5-2-13-27-16-22/h2,5-9,11,13,16,19,23,25H,3-4,10,12,14-15,17-18H2,1H3/t19-,23+,25-/m1/s1
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Similars
Article
PubMed
 1n/an/an/an/an/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membrane

Bioorg Med Chem Lett 18: 4133-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.05.086
BindingDB Entry DOI: 10.7270/Q2C82942
More data for this
Ligand-Target Pair