BDBM50243834 3-(1H-indol-5-yl)cyclohex-2-enone::CHEMBL449336
SMILES: O=C1CCCC(=C1)c1ccc2[nH]ccc2c1
InChI Key: InChIKey=LPSDOXKSOKFOEH-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calmodulin-sensitive adenylate cyclase (Bacillus anthracis) | BDBM50243834 (3-(1H-indol-5-yl)cyclohex-2-enone | CHEMBL449336) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas Medical Branch Curated by ChEMBL | Assay Description Inhibition of Bacilus anthracis edema factor-induced edema in RAW264.7 mouse macrophages by cAMP-specific ELISA | Bioorg Med Chem Lett 18: 4215-8 (2008) Article DOI: 10.1016/j.bmcl.2008.05.059 BindingDB Entry DOI: 10.7270/Q29G5MMN | |||||||||||
More data for this Ligand-Target Pair |