BDBM50243853 4-(3-(4-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-4-yl)piperazin-1-yl)propoxy)-1H-benzo[d]imidazole-2(3H)-thione::CHEMBL488812

SMILES: FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(CCCOc2cccc3[nH]c(=S)[nH]c23)CC1

InChI Key: InChIKey=BVRSVBDDYFIPRX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50243853   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50243853 (4-(3-(4-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-4...) Show SMILES FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(CCCOc2cccc3[nH]c(=S)[nH]c23)CC1 Show InChI InChI=1S/C22H23F3N6OS/c23-22(24,25)20-26-14-4-1-6-16(18(14)28-20)31-11-9-30(10-12-31)8-3-13-32-17-7-2-5-15-19(17)29-21(33)27-15/h1-2,4-7H,3,8-13H2,(H,26,28)(H2,27,29,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Binding affinity to human 5HT1A receptor				Bioorg Med Chem 16: 6617-40 (2008) Article DOI: 10.1016/j.bmc.2008.05.024 BindingDB Entry DOI: 10.7270/Q2FB52Q7
					More data for this Ligand-Target Pair
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50243853 (4-(3-(4-(2-(Trifluoromethyl)-1H-benzo[d]imidazol-4...) Show SMILES FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(CCCOc2cccc3[nH]c(=S)[nH]c23)CC1 Show InChI InChI=1S/C22H23F3N6OS/c23-22(24,25)20-26-14-4-1-6-16(18(14)28-20)31-11-9-30(10-12-31)8-3-13-32-17-7-2-5-15-19(17)29-21(33)27-15/h1-2,4-7H,3,8-13H2,(H,26,28)(H2,27,29,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptor				Bioorg Med Chem 16: 6617-40 (2008) Article DOI: 10.1016/j.bmc.2008.05.024 BindingDB Entry DOI: 10.7270/Q2FB52Q7
					More data for this Ligand-Target Pair