BDBM50244011 4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide::4'-[(R)-1-Amino-2-(2,5-difluoro-phenyl)-ethyl]-biphenyl-3-carboxylic acid amide::CHEMBL452289

SMILES: N[C@H](Cc1cc(F)ccc1F)c1ccc(cc1)-c1cccc(c1)C(N)=O

InChI Key: InChIKey=JYKFWUXBFJJDTP-HXUWFJFHSA-N

Data: 3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50244011 (4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphe...) Show SMILES N[C@H](Cc1cc(F)ccc1F)c1ccc(cc1)-c1cccc(c1)C(N)=O |r| Show InChI InChI=1S/C21H18F2N2O/c22-18-8-9-19(23)17(11-18)12-20(24)14-6-4-13(5-7-14)15-2-1-3-16(10-15)21(25)26/h1-11,20H,12,24H2,(H2,25,26)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem	MMDB PDB Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP4 (unknown origin)				Bioorg Med Chem Lett 18: 3706-10 (2008) Article DOI: 10.1016/j.bmcl.2008.05.061 BindingDB Entry DOI: 10.7270/Q24T6J6Q
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50244011 (4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphe...) Show SMILES N[C@H](Cc1cc(F)ccc1F)c1ccc(cc1)-c1cccc(c1)C(N)=O |r| Show InChI InChI=1S/C21H18F2N2O/c22-18-8-9-19(23)17(11-18)12-20(24)14-6-4-13(5-7-14)15-2-1-3-16(10-15)21(25)26/h1-11,20H,12,24H2,(H2,25,26)/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem	MMDB PDB Article	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of dipeptidyl peptidase 4 (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-012-0455-6 BindingDB Entry DOI: 10.7270/Q2HH6NZ4
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50244011 (4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphe...) Show SMILES N[C@H](Cc1cc(F)ccc1F)c1ccc(cc1)-c1cccc(c1)C(N)=O |r| Show InChI InChI=1S/C21H18F2N2O/c22-18-8-9-19(23)17(11-18)12-20(24)14-6-4-13(5-7-14)15-2-1-3-16(10-15)21(25)26/h1-11,20H,12,24H2,(H2,25,26)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP8 (unknown origin)				Bioorg Med Chem Lett 18: 3706-10 (2008) Article DOI: 10.1016/j.bmcl.2008.05.061 BindingDB Entry DOI: 10.7270/Q24T6J6Q
					More data for this Ligand-Target Pair