BDBM50244478 (Z)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethylene)-tetrahydrofuran-2-yl)methyl 4-methoxybenzoate::CHEMBL530337

SMILES: COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C\c2ccc3ccccc3n2)C(=O)O1

InChI Key: InChIKey=WLOFBQGIOLFGEO-PDGQHHTCSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAS guanyl releasing protein 3 (Homo sapiens (Human))	BDBM50244478 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C\c2ccc3ccccc3n2)C(=O)O1 Show InChI InChI=1S/C24H21NO6/c1-29-20-10-7-17(8-11-20)22(27)30-15-24(14-26)13-18(23(28)31-24)12-19-9-6-16-4-2-3-5-21(16)25-19/h2-12,26H,13-15H2,1H3/b18-12-	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cells				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50244478 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...) Show SMILES COc1ccc(cc1)C(=O)OCC1(CO)C\C(=C\c2ccc3ccccc3n2)C(=O)O1 Show InChI InChI=1S/C24H21NO6/c1-29-20-10-7-17(8-11-20)22(27)30-15-24(14-26)13-18(23(28)31-24)12-19-9-6-16-4-2-3-5-21(16)25-19/h2-12,26H,13-15H2,1H3/b18-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute at Frederick Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)				J Med Chem 51: 5371-86 (2008) Article DOI: 10.1021/jm800380b BindingDB Entry DOI: 10.7270/Q21V5DSQ
					More data for this Ligand-Target Pair