BDBM50244505 (R)-trans-3-{4-[1-(4-tert-Butylcyclohexyl)-3-(3,5-dimethylphenyl)ureidomethyl]benzoylamino}-2-hydroxypropionic acid::CHEMBL452067

SMILES: Cc1cc(C)cc(NC(=O)N(Cc2ccc(cc2)C(=O)NC[C@@H](O)C(O)=O)[C@H]2CC[C@@H](CC2)C(C)(C)C)c1

InChI Key: InChIKey=VLGOFRLXSHLEAO-LGPLSSKUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gastric inhibitory polypeptide receptor (Homo sapiens (Human))	BDBM50244505 ((R)-trans-3-{4-[1-(4-tert-Butylcyclohexyl)-3-(3,5-...) Show SMILES Cc1cc(C)cc(NC(=O)N(Cc2ccc(cc2)C(=O)NC[C@@H](O)C(O)=O)[C@H]2CC[C@@H](CC2)C(C)(C)C)c1 |r,wU:30.34,22.23,wD:27.27,(41.34,-18.77,;40.01,-19.54,;40.02,-21.09,;38.69,-21.86,;38.69,-23.4,;37.35,-21.1,;37.36,-19.55,;36.02,-18.79,;34.69,-19.56,;34.69,-21.1,;33.36,-18.79,;32.03,-19.56,;30.69,-18.79,;29.35,-19.57,;28.02,-18.8,;28.02,-17.25,;29.35,-16.48,;30.68,-17.24,;26.69,-16.48,;26.69,-14.94,;25.35,-17.25,;24.02,-16.48,;22.69,-17.25,;22.69,-18.79,;21.35,-16.48,;21.35,-14.94,;20.02,-17.25,;33.36,-17.25,;34.69,-16.48,;34.7,-14.95,;33.36,-14.18,;32.03,-14.95,;32.02,-16.49,;33.37,-12.64,;33.36,-11.09,;34.91,-12.63,;31.83,-12.64,;38.68,-18.78,)| Show InChI InChI=1S/C30H41N3O5/c1-19-14-20(2)16-24(15-19)32-29(38)33(25-12-10-23(11-13-25)30(3,4)5)18-21-6-8-22(9-7-21)27(35)31-17-26(34)28(36)37/h6-9,14-16,23,25-26,34H,10-13,17-18H2,1-5H3,(H,31,35)(H,32,38)(H,36,37)/t23-,25-,26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity to human cloned GIPR expressed in BHK cells				J Med Chem 51: 5387-96 (2008) Article DOI: 10.1021/jm7015599 BindingDB Entry DOI: 10.7270/Q2X34X9R
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50244505 ((R)-trans-3-{4-[1-(4-tert-Butylcyclohexyl)-3-(3,5-...) Show SMILES Cc1cc(C)cc(NC(=O)N(Cc2ccc(cc2)C(=O)NC[C@@H](O)C(O)=O)[C@H]2CC[C@@H](CC2)C(C)(C)C)c1 |r,wU:30.34,22.23,wD:27.27,(41.34,-18.77,;40.01,-19.54,;40.02,-21.09,;38.69,-21.86,;38.69,-23.4,;37.35,-21.1,;37.36,-19.55,;36.02,-18.79,;34.69,-19.56,;34.69,-21.1,;33.36,-18.79,;32.03,-19.56,;30.69,-18.79,;29.35,-19.57,;28.02,-18.8,;28.02,-17.25,;29.35,-16.48,;30.68,-17.24,;26.69,-16.48,;26.69,-14.94,;25.35,-17.25,;24.02,-16.48,;22.69,-17.25,;22.69,-18.79,;21.35,-16.48,;21.35,-14.94,;20.02,-17.25,;33.36,-17.25,;34.69,-16.48,;34.7,-14.95,;33.36,-14.18,;32.03,-14.95,;32.02,-16.49,;33.37,-12.64,;33.36,-11.09,;34.91,-12.63,;31.83,-12.64,;38.68,-18.78,)| Show InChI InChI=1S/C30H41N3O5/c1-19-14-20(2)16-24(15-19)32-29(38)33(25-12-10-23(11-13-25)30(3,4)5)18-21-6-8-22(9-7-21)27(35)31-17-26(34)28(36)37/h6-9,14-16,23,25-26,34H,10-13,17-18H2,1-5H3,(H,31,35)(H,32,38)(H,36,37)/t23-,25-,26-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity to human cloned GluR expressed in BHK cells				J Med Chem 51: 5387-96 (2008) Article DOI: 10.1021/jm7015599 BindingDB Entry DOI: 10.7270/Q2X34X9R
					More data for this Ligand-Target Pair