BDBM50244618 (2R,3S)-2,3-dihydroxy-N-((R)-6-(piperidin-1-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-4-(4-(trifluoromethyl)phenylsulfonyl)butanamide::CHEMBL455643

SMILES: O[C@H](CS(=O)(=O)c1ccc(cc1)C(F)(F)F)[C@@H](O)C(=O)N[C@@H]1CCCc2cc(CN3CCCCC3)ccc12

InChI Key: InChIKey=ZRLUSHCQXOZUBC-UBFVSLLYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50244618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50244618 ((2R,3S)-2,3-dihydroxy-N-((R)-6-(piperidin-1-ylmeth...) Show SMILES O[C@H](CS(=O)(=O)c1ccc(cc1)C(F)(F)F)[C@@H](O)C(=O)N[C@@H]1CCCc2cc(CN3CCCCC3)ccc12 |r| Show InChI InChI=1S/C27H33F3N2O5S/c28-27(29,30)20-8-10-21(11-9-20)38(36,37)17-24(33)25(34)26(35)31-23-6-4-5-19-15-18(7-12-22(19)23)16-32-13-2-1-3-14-32/h7-12,15,23-25,33-34H,1-6,13-14,16-17H2,(H,31,35)/t23-,24-,25-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	48.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]DAK from human bradykinin B1 receptor expressed in clone CHO-D-/aequorin cells				Bioorg Med Chem Lett 18: 4764-9 (2008) Article DOI: 10.1016/j.bmcl.2008.07.108 BindingDB Entry DOI: 10.7270/Q29C6X87
					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Homo sapiens (Human))	BDBM50244618 ((2R,3S)-2,3-dihydroxy-N-((R)-6-(piperidin-1-ylmeth...) Show SMILES O[C@H](CS(=O)(=O)c1ccc(cc1)C(F)(F)F)[C@@H](O)C(=O)N[C@@H]1CCCc2cc(CN3CCCCC3)ccc12 |r| Show InChI InChI=1S/C27H33F3N2O5S/c28-27(29,30)20-8-10-21(11-9-20)38(36,37)17-24(33)25(34)26(35)31-23-6-4-5-19-15-18(7-12-22(19)23)16-32-13-2-1-3-14-32/h7-12,15,23-25,33-34H,1-6,13-14,16-17H2,(H,31,35)/t23-,24-,25-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	44.9	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at human bradykinin B1 receptor expressed in clone CHO-D-/aequorin cells by aquerin based assay				Bioorg Med Chem Lett 18: 4764-9 (2008) Article DOI: 10.1016/j.bmcl.2008.07.108 BindingDB Entry DOI: 10.7270/Q29C6X87
					More data for this Ligand-Target Pair
Bradykinin B1 receptor (Oryctolagus cuniculus)	BDBM50244618 ((2R,3S)-2,3-dihydroxy-N-((R)-6-(piperidin-1-ylmeth...) Show SMILES O[C@H](CS(=O)(=O)c1ccc(cc1)C(F)(F)F)[C@@H](O)C(=O)N[C@@H]1CCCc2cc(CN3CCCCC3)ccc12 |r| Show InChI InChI=1S/C27H33F3N2O5S/c28-27(29,30)20-8-10-21(11-9-20)38(36,37)17-24(33)25(34)26(35)31-23-6-4-5-19-15-18(7-12-22(19)23)16-32-13-2-1-3-14-32/h7-12,15,23-25,33-34H,1-6,13-14,16-17H2,(H,31,35)/t23-,24-,25-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at rabbit bradykinin B1 receptor expressed in clone CHO-D-/aequorin cells by aquerin based assay				Bioorg Med Chem Lett 18: 4764-9 (2008) Article DOI: 10.1016/j.bmcl.2008.07.108 BindingDB Entry DOI: 10.7270/Q29C6X87
					More data for this Ligand-Target Pair