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SMILES: Cc1ncc(NC(=O)c2cc(NC(=O)c3cccc(Cl)c3)ccc2Cl)s1

InChI Key: InChIKey=MHUNFCOBOKSURA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50244843   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))		BDBM50244843
PNG
(2-Chloro-5-(3-chloro-benzoylamino)-N-(2-methyl-thi...)
Show SMILES Cc1ncc(NC(=O)c2cc(NC(=O)c3cccc(Cl)c3)ccc2Cl)s1
Show InChI InChI=1S/C18H13Cl2N3O2S/c1-10-21-9-16(26-10)23-18(25)14-8-13(5-6-15(14)20)22-17(24)11-3-2-4-12(19)7-11/h2-9H,1H3,(H,22,24)(H,23,25)
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Article
PubMed
n/an/a 4n/an/an/an/an/an/a



AstraZeneca R&D Boston

Curated by ChEMBL


Assay Description
Inhibition of CSF1R (unknown origin)

Bioorg Med Chem Lett 18: 4794-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.093
BindingDB Entry DOI: 10.7270/Q2028RCC
More data for this
Ligand-Target Pair