BDBM50245148 CHEMBL4077759

SMILES: CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cc(F)cc(c1)C(F)(F)F

InChI Key: InChIKey=JREQKSIAJGFHSM-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DCN1-UBC12 (Homo sapiens)	BDBM50245148 (CHEMBL4077759 | US11116757, No. A6) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C25H31F4N3O/c1-3-7-18(2)31-12-10-23(11-13-31)32(17-19-8-5-4-6-9-19)24(33)30-22-15-20(25(27,28)29)14-21(26)16-22/h4-6,8-9,14-16,18,23H,3,7,10-13,17H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DCN1-like protein 1 (Homo sapiens)	BDBM50245148 (CHEMBL4077759 | US11116757, No. A6) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1cc(F)cc(c1)C(F)(F)F Show InChI InChI=1S/C25H31F4N3O/c1-3-7-18(2)31-12-10-23(11-13-31)32(17-19-8-5-4-6-9-19)24(33)30-22-15-20(25(27,28)29)14-21(26)16-22/h4-6,8-9,14-16,18,23H,3,7,10-13,17H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
St. Jude Children's Research Hospital Curated by ChEMBL					Assay Description Inhibition of biotin-labeled DCN1 (unknown origin) assessed as reduction in protein interaction with Ac-UBE2M12-AlexaFluor488 after 1 hr by TR-FRET a...				J Med Chem 61: 2694-2706 (2018) Article DOI: 10.1021/acs.jmedchem.7b01282 BindingDB Entry DOI: 10.7270/Q22V2JHZ
					More data for this Ligand-Target Pair