BDBM50245166 (R)-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-hydroxypentan-3-yl)phenyl)piperazin-1-yl)-1-oxopropan-2-yl)-2-(dimethylamino)acetamide::CHEMBL454900

SMILES: CCC(O)(CC)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CN(C)C

InChI Key: InChIKey=JUZSSTZMGZLRNQ-XMMPIXPASA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50245166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50245166 ((R)-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-hydroxype...) Show SMILES CCC(O)(CC)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CN(C)C |r| Show InChI InChI=1S/C28H38Cl2N4O3/c1-5-28(37,6-2)22-9-7-8-10-25(22)33-13-15-34(16-14-33)27(36)24(31-26(35)19-32(3)4)17-20-11-12-21(29)18-23(20)30/h7-12,18,24,37H,5-6,13-17,19H2,1-4H3,(H,31,35)/t24-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to human MC4 receptor				Bioorg Med Chem Lett 18: 4817-22 (2008) Article DOI: 10.1016/j.bmcl.2008.07.076 BindingDB Entry DOI: 10.7270/Q24T6J75
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Homo sapiens (Human))	BDBM50245166 ((R)-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-hydroxype...) Show SMILES CCC(O)(CC)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CN(C)C |r| Show InChI InChI=1S/C28H38Cl2N4O3/c1-5-28(37,6-2)22-9-7-8-10-25(22)33-13-15-34(16-14-33)27(36)24(31-26(35)19-32(3)4)17-20-11-12-21(29)18-23(20)30/h7-12,18,24,37H,5-6,13-17,19H2,1-4H3,(H,31,35)/t24-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to MC5 receptor				Bioorg Med Chem Lett 18: 4817-22 (2008) Article DOI: 10.1016/j.bmcl.2008.07.076 BindingDB Entry DOI: 10.7270/Q24T6J75
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50245166 ((R)-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-hydroxype...) Show SMILES CCC(O)(CC)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CN(C)C |r| Show InChI InChI=1S/C28H38Cl2N4O3/c1-5-28(37,6-2)22-9-7-8-10-25(22)33-13-15-34(16-14-33)27(36)24(31-26(35)19-32(3)4)17-20-11-12-21(29)18-23(20)30/h7-12,18,24,37H,5-6,13-17,19H2,1-4H3,(H,31,35)/t24-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to MC3 receptor				Bioorg Med Chem Lett 18: 4817-22 (2008) Article DOI: 10.1016/j.bmcl.2008.07.076 BindingDB Entry DOI: 10.7270/Q24T6J75
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50245166 ((R)-N-(3-(2,4-dichlorophenyl)-1-(4-(2-(3-hydroxype...) Show SMILES CCC(O)(CC)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CN(C)C |r| Show InChI InChI=1S/C28H38Cl2N4O3/c1-5-28(37,6-2)22-9-7-8-10-25(22)33-13-15-34(16-14-33)27(36)24(31-26(35)19-32(3)4)17-20-11-12-21(29)18-23(20)30/h7-12,18,24,37H,5-6,13-17,19H2,1-4H3,(H,31,35)/t24-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human MC4 receptor expressed in cells assessed as inhibition of alpha-MSH-stimulated cAMP production				Bioorg Med Chem Lett 18: 4817-22 (2008) Article DOI: 10.1016/j.bmcl.2008.07.076 BindingDB Entry DOI: 10.7270/Q24T6J75
					More data for this Ligand-Target Pair