BindingDB PrimarySearch

BDBM50245180 3-(4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-4-carbonyl)piperazin-1-yl)-1-naphthoic acid::CHEMBL505409::CHEMBL505727

SMILES: CCOc1cccc(c1)-n1cc(nc1-c1ccc(C)cc1)C(=O)N1CCN(CC1)c1cc(C(O)=O)c2ccccc2c1

InChI Key: InChIKey=HMGSYODAZJHCRL-UHFFFAOYSA-N

Data: 3 IC50 4 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50245180
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50245180 (3-(4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0940	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity against human CCK1 receptor				Bioorg Med Chem Lett 18: 4393-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.057 BindingDB Entry DOI: 10.7270/Q2HH6JW0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50245180 (3-(4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human CCK2 receptor				Bioorg Med Chem Lett 18: 4393-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.057 BindingDB Entry DOI: 10.7270/Q2HH6JW0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (MOUSE)	BDBM50245180 (3-(4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity against mouse CCK1 receptor				Bioorg Med Chem Lett 18: 4393-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.057 BindingDB Entry DOI: 10.7270/Q2HH6JW0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50245180 (3-(4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of human CCK1 receptor				Bioorg Med Chem Lett 18: 4833-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.083 BindingDB Entry DOI: 10.7270/Q2RJ4J94
Merck & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Mus musculus)	BDBM50245180 (3-(4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at mouse CCK1 receptor				Bioorg Med Chem Lett 18: 4833-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.083 BindingDB Entry DOI: 10.7270/Q2RJ4J94
Merck & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50245180 (3-(4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0940	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Agonist activity at human CCK1 receptor				Bioorg Med Chem Lett 18: 4833-7 (2008) Article DOI: 10.1016/j.bmcl.2008.07.083 BindingDB Entry DOI: 10.7270/Q2RJ4J94
Merck & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50245180 (3-(4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-4-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human CCK1 receptor				Bioorg Med Chem Lett 18: 4393-6 (2008) Article DOI: 10.1016/j.bmcl.2008.06.057 BindingDB Entry DOI: 10.7270/Q2HH6JW0
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair