BDBM50245293 6-(6,7-dimethoxyquinolin-4-yloxy)-N-(4-methoxyphenyl)-1-methyl-1H-indazol-3-amine::CHEMBL460077

SMILES: COc1ccc(Nc2nn(C)c3cc(Oc4ccnc5cc(OC)c(OC)cc45)ccc23)cc1

InChI Key: InChIKey=FCOZEUAHNZKOTH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50245293 (6-(6,7-dimethoxyquinolin-4-yloxy)-N-(4-methoxyphen...) Show SMILES COc1ccc(Nc2nn(C)c3cc(Oc4ccnc5cc(OC)c(OC)cc45)ccc23)cc1 Show InChI InChI=1S/C26H24N4O4/c1-30-22-13-18(9-10-19(22)26(29-30)28-16-5-7-17(31-2)8-6-16)34-23-11-12-27-21-15-25(33-4)24(32-3)14-20(21)23/h5-15H,1-4H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant KDR by HTRF assay				Bioorg Med Chem Lett 18: 4844-8 (2008) Article DOI: 10.1016/j.bmcl.2008.07.080 BindingDB Entry DOI: 10.7270/Q2W9591V
					More data for this Ligand-Target Pair