Found 4 hits for monomerid = 50245408 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50245408
(CHEMBL461115 | N-(4-methoxyphenethyl)-4-amino-6-(4...)Show SMILES COc1ccc(CCNC(=O)c2c(N)ncnc2Nc2ccc(OCc3ccccc3)c(Cl)c2)cc1 Show InChI InChI=1S/C27H26ClN5O3/c1-35-21-10-7-18(8-11-21)13-14-30-27(34)24-25(29)31-17-32-26(24)33-20-9-12-23(22(28)15-20)36-16-19-5-3-2-4-6-19/h2-12,15,17H,13-14,16H2,1H3,(H,30,34)(H3,29,31,32,33) | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Inhibition of HER2 (unknown origin) |
Bioorg Med Chem Lett 18: 4896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.057 BindingDB Entry DOI: 10.7270/Q2NS0TPB |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50245408
(CHEMBL461115 | N-(4-methoxyphenethyl)-4-amino-6-(4...)Show SMILES COc1ccc(CCNC(=O)c2c(N)ncnc2Nc2ccc(OCc3ccccc3)c(Cl)c2)cc1 Show InChI InChI=1S/C27H26ClN5O3/c1-35-21-10-7-18(8-11-21)13-14-30-27(34)24-25(29)31-17-32-26(24)33-20-9-12-23(22(28)15-20)36-16-19-5-3-2-4-6-19/h2-12,15,17H,13-14,16H2,1H3,(H,30,34)(H3,29,31,32,33) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) |
Bioorg Med Chem Lett 18: 4896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.057 BindingDB Entry DOI: 10.7270/Q2NS0TPB |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM50245408
(CHEMBL461115 | N-(4-methoxyphenethyl)-4-amino-6-(4...)Show SMILES COc1ccc(CCNC(=O)c2c(N)ncnc2Nc2ccc(OCc3ccccc3)c(Cl)c2)cc1 Show InChI InChI=1S/C27H26ClN5O3/c1-35-21-10-7-18(8-11-21)13-14-30-27(34)24-25(29)31-17-32-26(24)33-20-9-12-23(22(28)15-20)36-16-19-5-3-2-4-6-19/h2-12,15,17H,13-14,16H2,1H3,(H,30,34)(H3,29,31,32,33) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Inhibition of CDK1 (unknown origin) |
Bioorg Med Chem Lett 18: 4896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.057 BindingDB Entry DOI: 10.7270/Q2NS0TPB |
More data for this Ligand-Target Pair | |
Aurora kinase A
(Homo sapiens (Human)) | BDBM50245408
(CHEMBL461115 | N-(4-methoxyphenethyl)-4-amino-6-(4...)Show SMILES COc1ccc(CCNC(=O)c2c(N)ncnc2Nc2ccc(OCc3ccccc3)c(Cl)c2)cc1 Show InChI InChI=1S/C27H26ClN5O3/c1-35-21-10-7-18(8-11-21)13-14-30-27(34)24-25(29)31-17-32-26(24)33-20-9-12-23(22(28)15-20)36-16-19-5-3-2-4-6-19/h2-12,15,17H,13-14,16H2,1H3,(H,30,34)(H3,29,31,32,33) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Inhibition of Aurora A (unknown origin) |
Bioorg Med Chem Lett 18: 4896-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.07.057 BindingDB Entry DOI: 10.7270/Q2NS0TPB |
More data for this Ligand-Target Pair | |