BDBM50245422 6-(6,7-dimethoxyquinolin-4-yloxy)-N-(2-methoxyphenyl)naphthalen-1-amine::CHEMBL459896

SMILES: COc1ccccc1Nc1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12

InChI Key: InChIKey=NDZVXPQPJNKPJT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50245422 (6-(6,7-dimethoxyquinolin-4-yloxy)-N-(2-methoxyphen...) Show SMILES COc1ccccc1Nc1cccc2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 Show InChI InChI=1S/C28H24N2O4/c1-31-26-10-5-4-8-23(26)30-22-9-6-7-18-15-19(11-12-20(18)22)34-25-13-14-29-24-17-28(33-3)27(32-2)16-21(24)25/h4-17,30H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Amgen, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant KDR by HTRF assay				Bioorg Med Chem Lett 18: 4844-8 (2008) Article DOI: 10.1016/j.bmcl.2008.07.080 BindingDB Entry DOI: 10.7270/Q2W9591V
					More data for this Ligand-Target Pair