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BDBM50245534 2-amino-N-((R)-1-(4-(2-(1-amino-3-methylbutyl)phenyl)piperazin-1-yl)-3-(2,4-dichlorophenyl)-1-oxopropan-2-yl)acetamide::CHEMBL487043

SMILES: CC(C)CC(N)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CN

InChI Key: InChIKey=ZLCVENSDUDRPGN-OZAIVSQSSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245534   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50245534
PNG
(2-amino-N-((R)-1-(4-(2-(1-amino-3-methylbutyl)phen...)
Show SMILES CC(C)CC(N)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CN |r|
Show InChI InChI=1S/C26H35Cl2N5O2/c1-17(2)13-22(30)20-5-3-4-6-24(20)32-9-11-33(12-10-32)26(35)23(31-25(34)16-29)14-18-7-8-19(27)15-21(18)28/h3-8,15,17,22-23H,9-14,16,29-30H2,1-2H3,(H,31,34)/t22?,23-/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human MC4 receptor


Bioorg Med Chem Lett 18: 4817-22 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.076
BindingDB Entry DOI: 10.7270/Q24T6J75
More data for this
Ligand-Target Pair