BDBM50245606 3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-2-methylbutyl)phenyl)piperazin-1-yl)-1-oxopropan-2-yl)propanamide::CHEMBL529449

SMILES: CCC(C)C(O)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CCN

InChI Key: InChIKey=CKZFLGNUSVLCLU-GRELRLAZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50245606 (3-amino-N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-h...) Show SMILES CCC(C)C(O)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CCN |r| Show InChI InChI=1S/C27H36Cl2N4O3/c1-3-18(2)26(35)21-6-4-5-7-24(21)32-12-14-33(15-13-32)27(36)23(31-25(34)10-11-30)16-19-8-9-20(28)17-22(19)29/h4-9,17-18,23,26,35H,3,10-16,30H2,1-2H3,(H,31,34)/t18?,23-,26?/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to human MC4 receptor				Bioorg Med Chem Lett 18: 4817-22 (2008) Article DOI: 10.1016/j.bmcl.2008.07.076 BindingDB Entry DOI: 10.7270/Q24T6J75
					More data for this Ligand-Target Pair