BDBM50245699 CHEMBL4083815

SMILES: Clc1ccccc1-c1nnc(s1)-n1c(nc2ccccc2c1=O)-c1ccccc1

InChI Key: InChIKey=GIWXHQOZHZWJPU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245699   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50245699 (CHEMBL4083815) Show SMILES Clc1ccccc1-c1nnc(s1)-n1c(nc2ccccc2c1=O)-c1ccccc1 Show InChI InChI=1S/C22H13ClN4OS/c23-17-12-6-4-10-15(17)20-25-26-22(29-20)27-19(14-8-2-1-3-9-14)24-18-13-7-5-11-16(18)21(27)28/h1-13H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. C. Patel Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibition of human EGFR preincubated for 5 mins with substrate followed by ATP addition measured after 30 mins by HTRF method				Bioorg Med Chem 25: 2713-2723 (2017) Article DOI: 10.1016/j.bmc.2017.03.039 BindingDB Entry DOI: 10.7270/Q2NP26TD
					More data for this Ligand-Target Pair