BDBM50245703 CHEMBL4103440

SMILES: COc1ccc(cc1)-c1nnc(s1)-n1c(nc2cc(Cl)ccc2c1=O)-c1ccccc1

InChI Key: InChIKey=IEKNZXAZPJJHMT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50245703 (CHEMBL4103440) Show SMILES COc1ccc(cc1)-c1nnc(s1)-n1c(nc2cc(Cl)ccc2c1=O)-c1ccccc1 Show InChI InChI=1S/C23H15ClN4O2S/c1-30-17-10-7-15(8-11-17)21-26-27-23(31-21)28-20(14-5-3-2-4-6-14)25-19-13-16(24)9-12-18(19)22(28)29/h2-13H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
R. C. Patel Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibition of human EGFR preincubated for 5 mins with substrate followed by ATP addition measured after 30 mins by HTRF method				Bioorg Med Chem 25: 2713-2723 (2017) Article DOI: 10.1016/j.bmc.2017.03.039 BindingDB Entry DOI: 10.7270/Q2NP26TD
					More data for this Ligand-Target Pair