BDBM50245705 CHEMBL4079183

SMILES: Clc1ccc2c(c1)nc(-c1ccccc1)n(-c1nnc(s1)C1CC1)c2=O

InChI Key: InChIKey=VPUZTPVLWZZOKN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50245705 (CHEMBL4079183) Show SMILES Clc1ccc2c(c1)nc(-c1ccccc1)n(-c1nnc(s1)C1CC1)c2=O Show InChI InChI=1S/C19H13ClN4OS/c20-13-8-9-14-15(10-13)21-16(11-4-2-1-3-5-11)24(18(14)25)19-23-22-17(26-19)12-6-7-12/h1-5,8-10,12H,6-7H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
R. C. Patel Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibition of human EGFR preincubated for 5 mins with substrate followed by ATP addition measured after 30 mins by HTRF method				Bioorg Med Chem 25: 2713-2723 (2017) Article DOI: 10.1016/j.bmc.2017.03.039 BindingDB Entry DOI: 10.7270/Q2NP26TD
					More data for this Ligand-Target Pair