BDBM50245734 9-hydroxy-6-(3-morpholinopropyl)-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL510668

SMILES: Oc1ccc2n(CCCN3CCOCC3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1

InChI Key: InChIKey=BVFLFSVYYYECQF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50245734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50245734 (9-hydroxy-6-(3-morpholinopropyl)-4-phenylpyrrolo[3...) Show SMILES Oc1ccc2n(CCCN3CCOCC3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1 Show InChI InChI=1S/C27H25N3O4/c31-18-7-8-21-20(15-18)23-22(30(21)10-4-9-29-11-13-34-14-12-29)16-19(17-5-2-1-3-6-17)24-25(23)27(33)28-26(24)32/h1-3,5-8,15-16,31H,4,9-14H2,(H,28,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determination				Eur J Med Chem 43: 1276-96 (2008) Article DOI: 10.1016/j.ejmech.2007.07.016 BindingDB Entry DOI: 10.7270/Q26M36MC
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase WEE1 (Homo sapiens (Human))	BDBM50245734 (9-hydroxy-6-(3-morpholinopropyl)-4-phenylpyrrolo[3...) Show SMILES Oc1ccc2n(CCCN3CCOCC3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1 Show InChI InChI=1S/C27H25N3O4/c31-18-7-8-21-20(15-18)23-22(30(21)10-4-9-29-11-13-34-14-12-29)16-19(17-5-2-1-3-6-17)24-25(23)27(33)28-26(24)32/h1-3,5-8,15-16,31H,4,9-14H2,(H,28,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylation				Eur J Med Chem 43: 1276-96 (2008) Article DOI: 10.1016/j.ejmech.2007.07.016 BindingDB Entry DOI: 10.7270/Q26M36MC
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50245734 (9-hydroxy-6-(3-morpholinopropyl)-4-phenylpyrrolo[3...) Show SMILES Oc1ccc2n(CCCN3CCOCC3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1 Show InChI InChI=1S/C27H25N3O4/c31-18-7-8-21-20(15-18)23-22(30(21)10-4-9-29-11-13-34-14-12-29)16-19(17-5-2-1-3-6-17)24-25(23)27(33)28-26(24)32/h1-3,5-8,15-16,31H,4,9-14H2,(H,28,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of c-Src				Eur J Med Chem 43: 1276-96 (2008) Article DOI: 10.1016/j.ejmech.2007.07.016 BindingDB Entry DOI: 10.7270/Q26M36MC
					More data for this Ligand-Target Pair