BDBM50245766 CHEMBL454917::N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-3-methylbutyl)phenyl)piperazin-1-yl)-1-oxopropan-2-yl)piperidine-3-carboxamide

SMILES: CC(C)CC(O)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)C1CCCNC1

InChI Key: InChIKey=UYENOMPDIPBYNL-MSBODSJQSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50245766 (CHEMBL454917 | N-((R)-3-(2,4-dichlorophenyl)-1-(4-...) Show SMILES CC(C)CC(O)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)C1CCCNC1 |r| Show InChI InChI=1S/C30H40Cl2N4O3/c1-20(2)16-28(37)24-7-3-4-8-27(24)35-12-14-36(15-13-35)30(39)26(17-21-9-10-23(31)18-25(21)32)34-29(38)22-6-5-11-33-19-22/h3-4,7-10,18,20,22,26,28,33,37H,5-6,11-17,19H2,1-2H3,(H,34,38)/t22?,26-,28?/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to human MC4 receptor				Bioorg Med Chem Lett 18: 4817-22 (2008) Article DOI: 10.1016/j.bmcl.2008.07.076 BindingDB Entry DOI: 10.7270/Q24T6J75
					More data for this Ligand-Target Pair